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Selected Recent Publications from Committee on Genetics Ph.D. candidates.

  • McMahill , MS, Sham CS, Bishop DK. (2007) Synthesis-dependent strand anneling in meiosis. PLoS Biol 2007 Nov 6;5(11):e299.
  • Lott SE, Kreitman, M. Palsson A, Alekseeva E, Ludwig MZ. Canalization of segmentation and its evolution in Drosophila. Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):10926-31.
  • Hilliker AK, Mefford, MA, Staley JP. U2 toggles iteratively between the stem IIa and stem IIc conformations to promote pre-mRNA splicing. Genes Dev. 2007 Apr 1;21(7):821-34.
  • Dai H, Yoshimatsu, T. & Long, MY.,(2006) รข??Retrogene movement within- and between-chromosomes in Evolution of Drosophila genomes. Gene, 2006 Dec 30;385:96-102. Epub 2006 Sep 23.
  • Evans PD, Gilbert SL, Mekel-Bobrov N, Vallender EJ, Anderson JR, Vaez-Azizi LM, Tishkoff SA, Hudson RR, Lahn BT. Microcephalin, a gene regulating brain size, continues to evolve adaptively in humans. Science. (2005) 309:1717-20.
  • Mekel-Bobrov N, Gilbert SL, Evans PD, Vallender EJ, Anderson JR, Hudson RR, Tishkoff SA, Lahn BT. Ongoing adaptive evolution of ASPM, a brain size determinant in Homo sapiens. Science. (2005) 309:1720-2.
  • Dorus S, Anderson JR, Vallender EJ, Gilbert SL, Zhang L, Chemnick LG, Ryder OA, Li W, Lahn BT. Sonic Hedgehog, a key development gene, experienced intensified molecular evolution in primates. Hum Mol Genet. (2006) 15:2031-7.
  • Evans PD, Vallender EJ, Lahn BT. Molecular evolution of the brain size regulator genes CDK5RAP2 and CENPJ. Gene. (2006) 375:75-9.
  • Vallender EJ, Lahn BT. A primate-specific acceleration in the evolution of the caspase-dependent apoptosis pathway. Hum Mol Genet. (2006) 15:3034-40.
  • Dorus S, Vallender EJ, Evans PD, Anderson JR, Gilbert SL, Mahowald M, Wyckoff GJ, Malcom CM, Lahn BT. Accelerated evolution of nervous system genes in the origin of Homo sapiens. Cell (2004)119:1027-40.
  • Thornton K, Long M. Excess of amino acid substitutions relative to polymorphism between X-linked duplications in Drosophila melanogaster. Mol Biol Evol. (2005) 22:273-84.
  • Hall, SE, Luo, S, Hall, AE, Preuss, D. Differential rates of local and global homogenization in centromere satellites from Arabidopsis relatives. Genetics. (2005) 4:1913-27.
  • Peng Y, Kang Q, Luo Q, Jiang W, Si W, Liu BA, Luu HH, Park JK, Li X, Luo J, Montag AG, Haydon RC, He TC. Inhibitor of DNA binding/differentiation helix-loop-helix proteins mediate bone morphogenetic protein-induced osteoblast differentiation of mesenchymal stem cells. J Biol Chem. (2004) 279:32941-9
  • Greenberg AJ, Moran JR, Fang S, Wu CI. Adaptive loss of an old duplicated gene during incipient speciation. Mol Biol Evol. (2006) 23:401-10
  • Fitz Gerald JN, Lehti-Shiu MD, Ingram PA, Deak KI, Biesiada T, Malamy JE. Identification of quantitative trait loci that regulate Arabidopsis root system size and plasticity. Genetics. (2006) 172:485-98.
  • Deak KI, Malamy J. Osmotic regulation of root system architecture. Plant J. (2005) 43:17-28.
  • Holzen TM, Shah PP, Olivares HA, Bishop DK. Tid1/Rdh54 promotes dissociation of Dmc1 from nonrecombinogenic sites on meiotic chromatin. Genes Dev. (2006) 20:2593-604.
  • Sheridan S, Bishop DK. Red-Hed regulation: recombinase Rad51, though capable of playing the leading role, may be relegated to supporting Dmc1 in budding yeast meiosis. Genes Dev. (2006)13:1685-91.
  • Chizhikov VV, Lindgren AG, Currle DS, Rose MF, Monuki ES, Millen KJ. The roof plate regulates cerebellar cell-type specification and proliferation. Development. (2006)133:2793-804.
  • Voight BF, Adams AM, Frisse LA, Qian Y, Hudson RR, Di Rienzo A. Interrogating multiple aspects of variation in a full resequencing data set to infer human population size changes. Proc Natl Acad Sci U S A. (2005) 102:18508-13.
  • Adams AM, Hudson RR. Maximum-likelihood estimation of demographic parameters using the frequency spectrum of unlinked single-nucleotide polymorphisms. Genetics. (2004) 168:1699-712.
  • Mewborn SK, Lese Martin C, Ledbetter DH. The dynamic nature and evolutionary history of subtelomeric and pericentromeric regions. Cytogenet Genome Res. (2005) 108:22-5.
  • Thompson, EE, Kuttab-Boulos, H., Yang, L., Roe, B.A, and Di Rienzo, A. Sequence diversity and haplotype structure at the human CYP3A cluster. (2006) Pharmacogenomics J. 6: 105-114

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