Ben May Department for Cancer Research
Du, Wei - Associate ProfessorCell cycle, tumor suppressor genes, and development.
Imamoto, Akira - Associate ProfessorMouse models of human syndromes affecting morphogenesis, patterning, and cell fate during craniofacial and cardiovascular development.
Jones, Richard - Assistant ProfessorSystems-Level Analyses of Cancer Signaling
Rebay, Ilaria - Associate ProfessorTranscriptional regulatory circuitries in development and disease; Receptor tyrosine kinase signal transduction.
Rosner, Marsha - ProfessorGrowth factor receptor signaling leading to cell growth, cell differentiation or cell death.
Biochemistry & Molecular Biophysics
Shapiro, James - ProfessorGenome reorganization and multicellular regulatory systems in bacteria populations.
Cancer Biology
Nash, Piers - Assistant ProfessorModular protein interaction domains in signal transduction and the cell cycle.
Cell & Molecular Biology
Fehon, Richard - ProfessorRegulation of epithelial polarity and proliferation during development.
Ferguson, Edwin - ProfessorDevelopmental genetics of cell fate specification and stem cell maintenance in Drosophila
Glick, Benjamin - ProfessorBiogenesis of secretory pathway organelles in yeast and mammalian cells, and directed evolution of fluorescent proteins.
Glotzer, Michael - Associate ProfessorThe molecular mechanism of cytokinesis in animal cells
Greenberg, Jean - ProfessorArabidopsis defense mechanisms against bacterial infection; Pseudomonas syringae virulence mechanisms.
Gupta, Mohan - Assistant Professor Mechanisms that regulate microtubule functions / interactions; roles of motor proteins in controlling microtubule dynamics; approaches range from in-vivo live cell imaging and functional assays to in-vitro single molecule analysis.
Haselkorn, Robert - ProfessorCellular differentiation in nitrogen-fixing cyanobacteria; acetyl CoA carboxylase in plants and humans and parasites.
Horne-Badovinac, Sally - Assistant ProfessorEpithelial morphogenesis and organ shape
Kovar, David - Assistant ProfessorBiochemical mechanisms of actin filament assembly.
Kron, Stephen - Associate ProfessorSignal transduction, cell cycle control, and checkpoints. Technology for proteomics, drug discovery and systems biology.
Lamppa, Gayle - Associate ProfessorChloroplast development; nuclear genes coding for chloroplast proteins; regulation of protein import and posttranslational processing.
Mahowald, Anthony - ProfessorDevelopmental genetics of oogenesis; ovarian germline stem cell; genetics of spermatogenesis.
Malamy, Jocelyn - Associate ProfessorMolecular regulation of root system growth and development in Arabidopsis and crop plants.
Mets, Laurens - Associate ProfessorChloroplast biogenesis and genetics; biochemical genetics and photophysics of photosynthesis; correlated genomic and genetic analysis.
Rothman-Denes, Lucia - ProfessorRNA polymerases structure and function; mechanisms of transcription regulation; host-viral interactions.
Singh, Harinder - ProfessorGene regulatory networks and the specification of cell fates in the immune system. Genetic engineering of stem cells.
Staley, Jonathan - Associate ProfessorPre-mRNA splicing: quality control, signal transduction, intron function and snRNA function. Approaches include genetics, genomics, cell biology and biochemistry in budding yeast.
Storb, Ursula - ProfessorImmunoglobulin gene expression; somatic hypermutation; regulation and functions of DNA methylation and chromatin modifications in development and transcription.
Strauss, Bernard - ProfessorMechanism of mutation; role of DNA polymerases in response to mutagenic agents.
Turkewitz, Aaron - Associate ProfessorSecretory granules; exocytosis and endocytosis; evolution of membrane traffic.
Ecology & Evolution
Bergelson, Joy - ProfessorThe evolution of plant-pathogen and plant-herbivore interactions; molecular ecology.
Borevitz, Justin - Assistant ProfessorQuantitative and population genetics of local native plant species
Hudson, Richard - ProfessorPopulation genetics theory and the analysis of molecular variation within and between populations.
Kreitman, Martin - ProfessorPopulation genetics; molecular evolution.
Li, Wen-Hsiung - ProfessorMolecular evolution, including experimental studies and bioinformatics studies of molecular and genomics.
Long, Manyuan - ProfessorNew gene evolution: the rates and patterns, the impact on protein networks, the functional and phenotypic effects; other problems of genome evolution. Drosophila as experimental systems; in silico genomics of animals and plants.
Nagylaki, Thomas - ProfessorTheoretical population biology, especially geographical variation; gene conversion in multi-gene families; random genetic drift; natural selection.
Price, Trevor - ProfessorGenetics of speciation, including molecular studies of gene flow, quantitative genetics of sexually selected traits, and comparative analyses using molecular phylogenies.
Ruvinsky, llya - Assistant ProfessorEvolution of development, particularly the evolution of transcriptional regulation (using C. elegans as a primary model organism); Comparative and computational genomics; Molecular evolution
Van Valen, Leigh - Professor Ecological and evolutionary genetics, organization and evolution of phenotype, evolution of development and adaptation, macroevolution, phylogenetics, conceptual analysis.
Wu, Chung-I - ProfessorSpeciation, genomics, evolutionary genetics, molecular population genetics, sexual selection.
Human Genetics
Di Rienzo, Anna - ProfessorHuman genetic variation and the evolution of common diseases.
Dobyns, William - ProfessorDevelopmental Neurogenetics, especially human brain development and the molecular genetics of brain malformations.
Gilad, Yoav - Assistant ProfessorEvolution of gene expression in primates; Evolution of the sense of smell.
Gilliam, Conrad - ProfessorOur group is generally focused upon identification of genetic determinants of common genetic disorders, with a particular emphasis on neurological and psychiatric genetic disease.
Lahn, Bruce - ProfessorEpigenetic Mechanisms of Cell Fate Restriction in Stem Cell Differentiation.
Millen, Kathleen - Associate ProfessorGenetic analysis vertebrate CNS development and the genetic basis of mental retardation and autism
Nobrega, Marcelo - Assistant ProfessorGenetics of heart development and congenital heart diseases. Genetic engineering of mouse models of human diseases. Genomic organization and gene regulatory architecture. Vertebrate comparative genomics.
Ober, Carole - ProfessorComplex trait genetics; QTL mapping; asthma; fertility
Palmer, Abraham - Assistant ProfessorGenetic basis of animal behavior, quantitative trait mapping, drug abuse and psychiatric phenotypes, translation of genetic findings to human populations
Pritchard, Jonathan - ProfessorStatistical genetics and population genetics; applications include complex disease mapping, human evolution and molecular evolution.
Przeworski, Molly - ProfessorPopulation genetics, human evolution
White, Kevin - ProfessorThe White lab studies the coordinated action of networks of genes that control developmental processes.
Medicine
Bell, Graeme - ProfessorGenetics of diabetes and other metabolic disorders; development and regeneration of insulin-secreting pancreatic beta cells
Cox, Nancy - ProfessorQuantitative human genetics, genetics of complex human diseases, including diabetes, asthma, stuttering, and psychiatric disorders.
Dolan, M. Eileen - ProfessorPharmacogenomics of Anticancer Agents
Ellis, Nathan - Associate ProfessorMolecular mechanisms that maintain genomic integrity, with special emphasis on the RecQ helicases; the genetics colon cancer susceptibility.
Le Beau, Michelle - ProfessorMolecular analysis of recurring chromosomal abnormalities in human tumors; identification of cooperating mutations and genetic pathways leading to transformation.
Lussier, Yves - Associate ProfessorFocus is on the use of computational systems biology and bioinformatics to accurately individualize the understanding, the prediction, and the treatment of disease.
McNally, Elizabeth - ProfessorGenetics of heart and muscle development and disease in humans and mice.
Olopade, Olufunmilayo (Funmi) - ProfessorCancer genetics and epigenetics, molecular genetics of breast and ovarian cancer; genetics of cancer predisposition in diverse populations including BRCA1 and BRCA2 genes, inflammation and cancer.
Refetoff, Samuel - ProfessorMolecular basis of inherited thyroid diseases.
Rowley, Janet - ProfessorChanges in gene expression in human leukemia cells with recurring chromosome translocations
Rzhetsky, Andrey - ProfessorAnalysis of complex molecular networks for understanding common phenotypes
Microbiology
Leber, Jess - Assistant ProfessorMy research investigates the mechanisms by which mammalian innate immunity recognizes intracellular infection, and the counter-measures used by intracellular pathogens to subvert host defenses.
Neurology
Popko, Brian - ProfessorMouse models in the study of neurological disorders.
Organismal Biology & Anatomy
Feder, Martin - ProfessorEvolutionary and ecological functional genomics, with Hsp70 and other molecular chaperones in Drosophila as a focus.
Ho, Robert - ProfessorPattern formation and early development in the simple vertebrate zebrafish.
Prince, Victoria - ProfessorMolecular, cellular, and comparative study of embryonic patterning along the anterior-posterior axis using zebrafish and other teleosts.
Schmidt-Ott, Urs - Assistant ProfessorDevelopmental Genetics and Evolution.
Pediatrics
Moskowitz, Ivan - Assistant ProfessorMolecular genetics of cardiovascular development and congenital heart disease.
Physics
Biron, David - Assistant ProfessorBehavior and neuroscience of the nematode C. elegans; Sleep-like behavior of C. elegans.
Psychiatry
Liu, Chun-Yu - Assistant ProfessorGenetics/genomics underlying neuropsychiatric disorders and brain functions.
Radiation & Cellular Oncology
Bishop, Douglas - ProfessorMeiotic recombination, recombinational DNA repair in yeast and mammalian cells.
Statistics
McPeek, Mary Sara - ProfessorApplications of probability and statistics to genetics; complex trait mapping; counting-process models for genetic recombination.
Surgery
He, Tong-Chuan - Associate ProfessorMolecular biology of bone and soft tissue tumors; BMP and Wnt signaling in stem cells; Regulation of mesenchymal stem cell differentiation; Cancer microenvironment and bone metastasis; Gene therapy and regenerative medicine.
Rinker-Schaeffer, Carrie - Associate ProfessorMolecular and mechanisims regulating cancer cell colonization of metastatic sites. Our work includes the areas of signal transduction, stress kinase activation, cell cycle progression, and novel mechanisms regulating metastatic growth including quorum sensing.