Ben May Department for Cancer Research

Du, Wei - Associate ProfessorCell cycle, tumor suppressor genes, and development.

Imamoto, Akira - Associate ProfessorMouse models of human syndromes affecting morphogenesis, patterning, and cell fate during craniofacial and cardiovascular development.

Jones, Richard - Assistant ProfessorSystems-Level Analyses of Cancer Signaling

Rebay, Ilaria - Associate ProfessorTranscriptional regulatory circuitries in development and disease; Receptor tyrosine kinase signal transduction.
Biochemistry & Molecular Biology

Shapiro, James - ProfessorGenome reorganization and multicellular regulatory systems in bacteria populations.
Ecology & Evolution

Bergelson, Joy - ProfessorThe evolution of plant-pathogen and plant-herbivore interactions; molecular ecology.

Borevitz, Justin - Assistant Professorquantitative and population genetics of Arabidopsis thaliana related to adaptation in natural light environments

Hudson, Richard - ProfessorPopulation genetics theory and the analysis of molecular variation within and between populations.

Kreitman, Martin - ProfessorPopulation genetics; molecular evolution.

Li, Wen-Hsiung - ProfessorMolecular evolution, including experimental studies and bioinformatics studies of molecular and genomics.

Long, Manyuan - ProfessorGenetics and evolution of Drosophila courtship behavior; Evolution of gene networks and systems driven by new genes; Rates and patterns of new gene origination; Other problems in molecular evolution and population genetics.

Nagylaki, Thomas - ProfessorTheoretical population biology, especially geographical variation; gene conversion in multi-gene families; random genetic drift; natural selection.

Price, Trevor - ProfessorGenetics of speciaiton, including molecular studies of gene flow, quantitaive genetics of sexually selected traits, and comparative analyses using molecular phylogenies.

Ruvinsky, llya - Assistant ProfessorEvolution of development, particularly the origin and diversification of the nervous system and evolution of transcriptional regulation (using C. elegans as a primary model organism); Comparative and computational genomics; Molecular evolution

Van Valen, Leigh - Professor Ecological and evolutionary genetics, organization and evolution of phenotype, evolution of development and adaptation, macroevolution, phylogenetics, conceptual analysis.

Wu, Chung-I - ProfessorSpeciation, genomics, evolutionary genetics, molecular population genetics, sexual selection.
Human Genetics

Di Rienzo, Anna - ProfessorHuman genetic variation and the evolution of common diseases.

Dobyns, William - ProfessorDevelopmental Neurogenetics, especially human brain development and the molecular genetics of brain malformations.

Gilad, Yoav - Assistant ProfessorEvolution of gene expression in primates; Evolution of the sense of smell.

Gilliam, Conrad - ProfessorOur group is generally focused upon identification of genetic determinants of common genetic disorders, with a particular emphasis on neurological and psychiatric genetic disease.

Lahn, Bruce - ProfessorHuman evolutionary genetics, genomics, bioinformatics, neurogenetics, and stem cell biology.

Millen, Kathleen - Associate ProfessorGenetic analysis of pattern formation during vertebrate CNS development and the genetic basis of congenital brain malformations in humans.

Nobrega, Marcelo - Assistant ProfessorGenetics of heart development and congenital heart diseases. Genetic engineering of mouse models of human diseases. Genomic organization and gene regulatory architecture. Vertebrate comparative genomics.

Ober, Carole - ProfessorComplex trait genetics; human population genetics; HLA and fertility.

Palmer, Abraham - Assistant ProfessorGenetic basis of animal behavior, quantitative trait mapping, drug abuse and psychiatric phenotypes, translation of genetic findings to human populations

Pritchard, Jonathan - ProfessorStatistical genetics and population genetics; applications include complex disease mapping, human evolution and molecular evolution.

Przeworski, Molly - Assistant ProfessorPopulation genetics, human evolution

White, Kevin - ProfessorThe White lab studies the coordinated action of networks of genes that control developmental processes.
Medicine

Bell, Graeme - ProfessorGenetics of diabetes and other metabolic disorders; development and regeneration of insulin-secreting pancreatic beta cells

Cox, Nancy - ProfessorQuantitative human genetics, genetics of complex human diseases, including diabetes, asthma, stuttering, and psychiatric disorders.

Dolan, M. Eileen - ProfessorPharmacogenomics of Anticancer Agents

Ellis, Nathan - Associate ProfessorMolecular mechanisms that maintain genomic integrity, with special emphasis on the RecQ helicases; the genetics colon cancer susceptibility.

Le Beau, Michelle - ProfessorMolecular analysis of recurring chromosomal abnormalities in human tumors; identification of cooperating mutations and genetic pathways leading to transformation.

McNally, Elizabeth - ProfessorGenetics of heart and muscle development and disease in humans and mice.

Olopade, Olufunmilayo (Funmi) - ProfessorCancer genetics and epigenetics, molecular genetics of breast and ovarian cancer; genetics of cancer predisposition in diverse populations including BRCA1 and BRCA2 genes, inflammation and cancer.

Refetoff, Samuel - ProfessorMolecular basis of inherited thyroid diseases.

Rowley, Janet - ProfessorChanges in gene expression in human leukemia cells with recurring chromosome translocations

Rzhetsky, Andrey - ProfessorAnalysis of complex molecular networks for understanding common phenotypes

Scanu, Angelo - ProfessorGenetic mechanisms in dyslipoproteinemias in humans; metalloproteinases and kringle-containing proteins; proteoglycans in atherogenesis.
Molecular Genetics & Cell Biology

Casadaban, Malcolm - Associate ProfessorGene structure and regulation; gene fusing, cloning and engineering; DNA transposition and mutator phage; nonhomologous recombination.

Fehon, Richard - ProfessorRegulation of epithelial polarity and proliferation during development.

Ferguson, Edwin - Associate ProfessorDevelopmental genetics of cell fate specification and stem cell maintenance in Drosophila

Glick, Benjamin - ProfessorBiogenesis of secretory pathway organelles in yeast and mammalian cells, and directed evolution of fluorescent proteins.

Glotzer, Michael - Associate ProfessorThe molecular mechanism of cytokinesis in animal cells.

Greenberg, Jean - Associate ProfessorArabidopsis defense mechanisms against bacterial infection; Pseudomonas syringae virulence mechanisms.

Haselkorn, Robert - ProfessorCellular differentiation in nitrogen-fixing cyanobacteria; acetyl CoA carboxylase in plants and humans.

Kovar, David - Assistant ProfessorMolecular mechanisms of actin assembly in fission yeast: molecular genetic to in vitro single filament studies.

Kron, Stephen - Associate ProfessorSignal transduction, cell cycle control, and checkpoints. Technology for proteomics, drug discovery and systems biology.

Lamppa, Gayle - Associate ProfessorChloroplast development; nuclear genes coding for chloroplast proteins; regulation of protein import and posttranslational processing.

Mahowald, Anthony - ProfessorDevelopmental genetics of oogenesis; ovarian germline stem cell; genetics of spermatogenesis.

Malamy, Jocelyn - Associate ProfessorMolecular regulation of root system growth and development in Arabidopsis and crop plants.

Mets, Laurens - Associate ProfessorChloroplast biogenesis and genetics; biochemical genetics and photophysics of photosynthesis; correlated genomic and genetic analysis.

Preuss, Daphne - ProfessorGenetic analysis of fertilization in Arabidopsis reproduction. Structure and function of plant centromeres.

Roizman, Bernard - ProfessorHerpes simplex viruses, gene function and regulation, mechanisms of latent infection, vectors for gene therapy.

Rothman-Denes, Lucia - ProfessorRNA polymerases structure and function; mechanisms of transcription regulation; host-viral interactions.

Singh, Harinder - ProfessorGene regulatory networks and the specification of cell fates in the immune system. Genetic engineering of stem cells.

Staley, Jonathan - Associate ProfessorPre-mRNA splicing: quality control, signal transduction, intron function and snRNA function. Approaches include genetics, genomics, cell biology and biochemistry in budding yeast.

Storb, Ursula - ProfessorImmunoglobulin gene expression; somatic hypermutation; regulation and functions of DNA methylation and chromatin modifications in development and transcription.

Strauss, Bernard - ProfessorMechanism of mutation; role of DNA polymerases in response to mutagenic agents.

Turkewitz, Aaron - Associate ProfessorSecretory granules; exocytosis and endocytosis; evolution of membrane traffic.
Neurology

Popko, Brian - ProfessorMouse models in the study of neurological disorders.
Opthalmology & Visual Science

McLeod, Rima - ProfessorImmunobiology of toxoplasmosis.
Organismal Biology & Anatomy

Feder, Martin - ProfessorEvolutionary and ecological functional genomics, with Hsp70 and other molecular chaperones in Drosophila as a focus.

Ho, Robert - ProfessorPattern formation and early development in the simple vertebrate zebrafish.

Prince, Victoria - Associate ProfessorMolecular, cellular, and comparative study of embryonic patterning along the anterior-posterior axis using zebrafish and other teleosts.

Schmidt-Ott, Urs - Assistant ProfessorDevelopmental Genetics and Evolution.
Pediatrics

Moskowitz, Ivan - Assistant ProfessorMolecular genetics of cardiovascular development and congenital heart disease.
Pshychiatry

Liu, Chun-Yu - Assistant ProfessorGenetics/genomics underlying neuropsychiatric disorders.
Radiation & Cellular Oncology

Bishop, Douglas - ProfessorMeiotic recombination, recombinational DNA repair in yeast and mammalian cells.
Statistics

McPeek, Mary Sara - ProfessorApplications of probability and statistics to genetics; complex trait mapping; counting-process models for genetic recombination.
Surgery

He, Tong-Chuan - Associate ProfessorMolecular biology of bone and soft tissue tumors; BMP and Wnt-regulated differentiation of mesenchymal stem cells; Cancer bone metastasis; Gene therapy.

Rinker-Schaeffer, Carrie - Associate ProfessorMolecular and mechanisims regulating cancer cell colonization of metastatic sites. Our work includes the areas of signal transduction, stress kinase activation, cell cycle progression, and novel mechanisms regulating metastatic growth including quorum sensing.