Bruce Lahn

Our lab is interested in developing and applying innovative genetic approaches to the study of mammalian development and evolution, with an emphasis on stem cell biology, epigenetics and evolutionary biology.

For details of our research, please goto our lab's web site at:
http://genes.uchicago.edu/lahn.html (this link is provided at the top of the page).

Our lab is interested in developing and applying innovative genetic approaches to the study of mammalian development and evolution, with an emphasis on stem cell biology, epigenetics and evolutionary biology.

For details of our research, please goto our lab's web site at:
http://genes.uchicago.edu/lahn.html (this link is provided at the top of the page).

Lee JH, Gaetz J, Bugarija B, Fernandes CJ, Snyder GE, Bush EC, Lahn BT. (2009). “Chromatin analysis of occluded genes.” Hum Mol Genet. 2009 Jul 15;18(14):2567-74. 

Park D, Xiang AP, Zhang L, Mao FF, Walton NM, Choi SS, Lahn BT (2009). The radial glia antibody RC2 recognizes a protein encoded by Nestin. Biochem Biophys Res Commun. 2009 May 8;382(3):588-92.  

Ke H, Wang P, Yu W, Liu X, Liu C, Yang F, Mao FF, Zhang L, Zhang X, Lahn BT, Xiang AP. (2009). Derivation, characterization and gene modification of cynomolgus monkey mesenchymal stem cells. Differentiation. 2009 Mar;77(3):256-62.  

Lee JH, Bugarija B, Millan EJ, Walton NM, Gaetz J, Fernandes CJ, Yu WH, Mekel-Bobrov N, Vallender TW, Snyder GE, Xiang AP, Lahn BT. (2009). Systematic identification of cis-silenced genes by trans complementation. Hum Mol Genet. 2009 Mar 1;18(5):835-46.  

Vallender EJ, Mekel-Bobrov N, Lahn BT. (2008). Genetic basis of human brain evolution. Trends Neurosci. 2008 Dec;31(12):637-44.  

Peng Y, Chen Z, Yu W, Zhou Q, Xu L, Mao FF, Huang G, Zhang X, Li S, Lahn BT, Xiang AP. (2008). Effects of thymic polypeptides on the thymopoiesis of mouse embryonic stem cells. Cell Biol Int. 2008 Oct;32(10):1265-71.  

Wang P, Liu XM, Liu XM, Ma BF, Jia L, Wang D, Zhang XM, Yu XB, Lahn BT, Xiang AP. (2008). Isolation, characterization and gene modification of fetal neural stem/progenitor cells from cynomolgus monkey. Neuroreport. 2008 Mar 5;19(4):419-24.  

Bush EC, Lahn BT. (2008). A genome-wide screen for noncoding elements important in primate evolution. BMC Evol Biol. 2008 Jan 23;8:17.  

Hawks J, Cochran G, Harpending HC, Lahn BT. (2008) A genetic legacy from archaic Homo. Trends Genet. 2008 Jan;24(1):19-23.  

Yu W, Chen Z, Zhang J, Zhang L, Ke H, Huang L, Peng Y, Zhang X, Li S, Lahn BT, Xiang AP.(2008). Critical role of phosphoinositide 3-kinase cascade in adipogenesis of human mesenchymal stem cells. Mol Cell Biochem. 2008 Mar;310(1-2):11-8.  

Lee JH, Gaetz J, Bugarija B, Fernandes CJ, Snyder GE, Bush EC, Lahn BT. (2009). “Chromatin analysis of occluded genes.” Hum Mol Genet. 2009 Jul 15;18(14):2567-74. 

Park D, Xiang AP, Zhang L, Mao FF, Walton NM, Choi SS, Lahn BT (2009). The radial glia antibody RC2 recognizes a protein encoded by Nestin. Biochem Biophys Res Commun. 2009 May 8;382(3):588-92.  

Ke H, Wang P, Yu W, Liu X, Liu C, Yang F, Mao FF, Zhang L, Zhang X, Lahn BT, Xiang AP. (2009). Derivation, characterization and gene modification of cynomolgus monkey mesenchymal stem cells. Differentiation. 2009 Mar;77(3):256-62.  

Lee JH, Bugarija B, Millan EJ, Walton NM, Gaetz J, Fernandes CJ, Yu WH, Mekel-Bobrov N, Vallender TW, Snyder GE, Xiang AP, Lahn BT. (2009). Systematic identification of cis-silenced genes by trans complementation. Hum Mol Genet. 2009 Mar 1;18(5):835-46.  

Vallender EJ, Mekel-Bobrov N, Lahn BT. (2008). Genetic basis of human brain evolution. Trends Neurosci. 2008 Dec;31(12):637-44.